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JPM Week 2026

At our first JPM Week, we discovered more than just meetings and momentum. We found validation for our mission and clarity around what continuous Parkinson’s care truly requires. Here are five lessons that changed everything for ActualSignal.
Hanan Iserovich

By Hanan Iserovich

The Week That Changed Everything: JPM Week 2026


When we arrived in San Francisco for JPM Week, we weren’t entirely sure we belonged there yet.

As an early stage company, it’s easy to wonder if the timing is right. Are we too early. Too small. Too unknown. JPM Week has a reputation for being overwhelming, crowded, and dominated by the biggest names in healthcare.

What we didn’t expect was just how transformative the experience would be.

Looking back now, our first JPM Week wasn’t just worth it. It was a turning point. Here are five lessons we took away from navigating the chaos.

1. The 10 Meeting Rule Is Real

JPM Week is not a place to see what happens.

The pace is relentless, calendars fill quickly, and meaningful conversations don’t happen by accident. Tools like RESI are incredibly valuable, but only if you use them with intention. For us, the biggest lesson was simple. If you’re not walking into the week with at least ten pre scheduled meetings, you’re leaving too much to chance.

Planning early made all the difference. JPM Week rewards preparation, not optimism.

2. The Energy Around Union Square Is the Ecosystem

Something magical happens when the entire healthcare innovation ecosystem compresses into a few square blocks.

Some of our most impactful conversations didn’t happen in conference rooms at all. They happened in elevators. In coffee lines. Standing on crowded sidewalks between meetings. Union Square becomes a living, breathing network of builders, clinicians, operators, and partners all focused on the same question. How do we make healthcare better.

If you’re building in health, you can feel it instantly. That energy is infectious, and it pulls you into bigger thinking.

3. The Why Landed Immediately

One of the most validating moments of the week was how quickly people understood our core belief.

Parkinson’s disease cannot be managed effectively with snapshots taken once or twice a year. Continuous conditions demand continuous care. When we talked about monitoring Parkinson’s daily instead of every six months, the response was immediate and consistent.

People saw it. They understood that earlier visibility means earlier intervention. That earlier intervention improves lives. And that improving lives is also how you reduce downstream healthcare costs.

That alignment clinical impact and system sustainability was powerful to witness.

4. It’s All About the FUP Follow Up

It’s tempting to think the week itself is the goal. It isn’t.

The real work starts the following Monday.

JPM Week opens doors, but only follow up turns conversations into relationships. You have to be ready to respond quickly, thoughtfully, and with purpose. Momentum fades fast if you don’t honor it.

For us, the lesson was clear. Treat JPM Week as the start of a process, not the finish line.

5. Our Mission Is Real

Perhaps the most meaningful takeaway of all was this. Our mission isn’t just aspirational. It resonates.

At ActualSignal, we talk about the responsibility to see every patient. That means seeing what happens between visits. Seeing subtle changes before they become emergencies. Seeing people before they become statistics.

Throughout the week, that message landed again and again. Every conversation reinforced that what we’re building isn’t just innovative. It’s necessary.

Every data point we collect is more than information. It’s an opportunity for earlier action, better decisions, and fewer hospitalizations. It’s a step toward care that’s proactive, not reactive.

Looking Ahead

JPM Week was loud, crowded, and exhausting, and we wouldn’t trade it for anything.

It challenged us, sharpened our thinking, and confirmed that we’re building something that matters. As we reflect on that week now, one thing is clear. The chaos had clarity hidden inside it.

And we’re more committed than ever to what comes next.

Because seeing patients earlier changes outcomes. And seeing what others miss changes everything.

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